give up
With or without an object
Stop doing something, or stop trying
She gave up smoking in 2019.
Stop trying
Do not give up! You are nearly there.
With or without an object
It can be used with no object, and it can also take one. With an object it is usually separable: turn the volume up, turn it up.
Related idiom
Read the meaning and origin of a related expression on The Village Idiom.
Practise it
Add it to your daily practice or see every verb with up.
Further reading: give up on Wiktionary (CC BY-SA).